ORIGINAL PAPER
Correlation between vitamin D level and idiopathic scoliosis development in an adolescent population: early detection
1
Department of Health and Rehabilitation Sciences, Prince Sattam bin Abdulaziz University, Alkharj, Saudi Arabia
2
Department of Physical Therapy for Paediatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt
3
Department of Basic Science, Faculty of Physical Therapy, South Valley University, Qena, Egypt
4
Department of Physical Therapy Musculoskeletal Disorders and Its Surgery, Faculty of Physical Therapy, South Valley University, Qena, Egypt
5
Department of Physical Therapy for Internal Medicine, Faculty of Physical Therapy, South Valley University, Qena, Egypt
6
Faculty of Applied Medical Sciences, Jerash University, Jordan
Submission date: 2024-05-27
Acceptance date: 2024-10-02
Online publication date: 2025-11-25
Corresponding author
Mshari Alghadier
Department of Health and Rehabilitation Sciences, Prince Sattam bin Abdulaziz University, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University Alkharj 11942, Saudi Arabia
Department of Health and Rehabilitation Sciences, Prince Sattam bin Abdulaziz University, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University Alkharj 11942, Saudi Arabia
KEYWORDS
TOPICS
ABSTRACT
Objective:
Adolescent idiopathic scoliosis (AIS) is the most common spinal deformity and has unclear aetiology. Vitamin D deficiency may contribute to AIS through its impact on bone metabolism. This study examined the correlation between vitamin D levels and idiopathic scoliosis development in an adolescent patient population.
Methods:
The study involved 130 patients (aged 7 to 18 years) diagnosed with AIS at a Physiotherapy and Rehabilitation Centre in Qena, Egypt, between May 2021 and October 2022. Patients’ clinical and demographic data were extracted from medical records, including age, gender, height, weight, serum vitamin D level, and Cobb angle. Scoliosis was identified when the Cobb angle was ≥ 10°.
Results:
Patients’ mean age was 13.1 ± 2.75 years, vitamin D level was 10.3 ng/ml ± 4.76, and weight was 47.4 kg ± 9.63. In the patient group, the mean Cobb angle was 16.8 ± 5.79°, with a 95 % confidence interval (CI) of 15.8–17.8. Vitamin D levels correlated positively with age (r = 0.45, p < 0.001) and weight (r = 0.51, p < 0.001). However, only a weak positive correlation was found between vitamin D and the Cobb angle (r = 0.11, p = 0.18).
Conclusions:
Vitamin D deficiency may contribute to AIS pathogenesis by affecting calcium and phosphorus metabolism in bone. As a result, we recommend testing vitamin D levels in those with AIS. Although there was only a positive weak correlation (not significant) between vitamin D levels and Cobb angle, vitamin D deficiency/insufficiency should be examined in AIS patients.
Adolescent idiopathic scoliosis (AIS) is the most common spinal deformity and has unclear aetiology. Vitamin D deficiency may contribute to AIS through its impact on bone metabolism. This study examined the correlation between vitamin D levels and idiopathic scoliosis development in an adolescent patient population.
Methods:
The study involved 130 patients (aged 7 to 18 years) diagnosed with AIS at a Physiotherapy and Rehabilitation Centre in Qena, Egypt, between May 2021 and October 2022. Patients’ clinical and demographic data were extracted from medical records, including age, gender, height, weight, serum vitamin D level, and Cobb angle. Scoliosis was identified when the Cobb angle was ≥ 10°.
Results:
Patients’ mean age was 13.1 ± 2.75 years, vitamin D level was 10.3 ng/ml ± 4.76, and weight was 47.4 kg ± 9.63. In the patient group, the mean Cobb angle was 16.8 ± 5.79°, with a 95 % confidence interval (CI) of 15.8–17.8. Vitamin D levels correlated positively with age (r = 0.45, p < 0.001) and weight (r = 0.51, p < 0.001). However, only a weak positive correlation was found between vitamin D and the Cobb angle (r = 0.11, p = 0.18).
Conclusions:
Vitamin D deficiency may contribute to AIS pathogenesis by affecting calcium and phosphorus metabolism in bone. As a result, we recommend testing vitamin D levels in those with AIS. Although there was only a positive weak correlation (not significant) between vitamin D levels and Cobb angle, vitamin D deficiency/insufficiency should be examined in AIS patients.
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