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ORIGINAL PAPER
Effects of a structured exercise therapy on health-related quality of life in pediatric stem cell transplantation
1
School for Health Science, University of Cooperative Education, Darmstadt, Germany
2
Medical School, Fresenius University of Applied Sciences, Frankfurt, Germany
3
Department of Pediatrics, University Cancer Center, Frankfurt, Germany
Submission date: 2023-08-21
Acceptance date: 2023-11-07
Publication date: 2024-09-09
Corresponding author
Michael Wilhelm Jung
School for Health Science, University of Cooperative Education, Poststr. 4-6, D-64293 Darmstadt, Germany
School for Health Science, University of Cooperative Education, Poststr. 4-6, D-64293 Darmstadt, Germany
Physiother Quart. 2024;32(3):29-39
KEYWORDS
TOPICS
ABSTRACT
Introduction:
This randomized controlled trial investigated the effects of exercise therapy on cancer-related fatigue (CRF) and its association with health-related quality of life. The effect of exercise therapy on the quality of life of children after stem cell transplantation has not been extensively studied to date.
Methods:
Seventy-two children and adolescents after stem cell transplantation were randomly assigned to either an exercise therapy intervention group (IG) or a control group (CG). The children in IG received sports therapy, while the children in the CG engaged in concentration tasks, memory games, and quizzes.
Results:
Significant improvements in CRF were found in IG only after discharge from the hospital. The improved CRF correlated significantly with increased health-related quality of life. However, during the inpatient phase, there was a rapid increase in CRF initially, which was accompanied by a significant reduction in health-related quality of life.
Conclusions:
Exercise therapy can help reduce CRF and, therefore, increase health-related quality of life after the inpatient phase.
This randomized controlled trial investigated the effects of exercise therapy on cancer-related fatigue (CRF) and its association with health-related quality of life. The effect of exercise therapy on the quality of life of children after stem cell transplantation has not been extensively studied to date.
Methods:
Seventy-two children and adolescents after stem cell transplantation were randomly assigned to either an exercise therapy intervention group (IG) or a control group (CG). The children in IG received sports therapy, while the children in the CG engaged in concentration tasks, memory games, and quizzes.
Results:
Significant improvements in CRF were found in IG only after discharge from the hospital. The improved CRF correlated significantly with increased health-related quality of life. However, during the inpatient phase, there was a rapid increase in CRF initially, which was accompanied by a significant reduction in health-related quality of life.
Conclusions:
Exercise therapy can help reduce CRF and, therefore, increase health-related quality of life after the inpatient phase.
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