ORIGINAL PAPER
Effect of repetitive transcranial magnetic stimulation on vestibular function and self-rated functional recovery in patients with peripheral vestibular dysfunction: a controlled clinical trial
1
Physical Therapy Department, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman, Jordan
2
Neurology department, Faculty of Medicine, Cairo University, Giza, Egypt
3
Clinical Neurophysiolgy Unit, Neurology department, Faculty of Medicine, Cairo University, Giza, Egypt
4
Audiovestibular Medicine, Kasr Al-Aini Hospital, Cairo University, Giza, Egypt
5
Department of Physical Therapy for Neuromuscular Disorders and Its Surgeries, Faculty of Physical Therapy, Cairo University, Giza, Egypt
6
Department of Basic Sciences, Faculty of Physical Therapy, Beni-Suef University, Beni-Suef, Egypt
7
Department of Physical Therapy for Cardiovascular and Respiratory Disorders and Geriatrics, Faculty of Physical Therapy, Beni-Suef University, Beni-Suef, Egypt
Submission date: 2024-01-27
Acceptance date: 2024-11-11
Online publication date: 2025-11-28
Corresponding author
Hosam Magdy Metwally Abd Alhamid
Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Al-Saro, Al-Salt, Amman, Jordan
Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Al-Saro, Al-Salt, Amman, Jordan
KEYWORDS
vestibular dysfunctionrepetitive transcranial magnetic stimulationvestibular physical therapy modalitiesvertigo
TOPICS
ABSTRACT
Introduction:
Most patients with vestibular dysfunction have balance disorders and vertigo, which may have a negative impact on the activities of daily living. This study aimed to investigate the effects of repetitive transcranial magnetic stimulation (TMS) on functional recovery in these patients.
Methods:
Thirty-five patients with unilateral peripheral vestibular dysfunction participated in this study. This study used a prospective randomised controlled trial design, and the randomisation was 1:1. They were randomly assigned to experimental and control groups; the experimental group, which consists of eighteen patients, received repetitive transcranial magnetic stimulation plus conventional physical therapy treatment in the form of Cawthorne-Cooksey exercises, while the control group, which consists of seventeen patients, received only conventional physical therapy treatment. The interventions in the two groups were conducted in three sessions every week for four consecutive weeks. The primary outcome measure was videonystagmography. The chi-squared and a mixed-design 2 × 2 MANOVA test were used to compare differences in variables for evaluating baseline and post-treatment changes.
Results:
The experimental group showed a significant improvement in canal weakness (66.26%) with a p < 0.001, DHI (77.21%) with a p-value of 0.001, and VADL (70.85%) with a p-value of 0.003 as compared to the controls. The control group showed significant improvements only in the DHI (44.45%) and VADL (33.05%) compared to the baseline, and the effect size f2 (V) = 0.66 was calculated for the independent canal weakness variable.
Conclusions:
The addition of repetitive transcranial magnetic stimulation to Cawthorne-Cooksey exercises could improve the outcomes of vestibular and self-rated functional recovery.
Most patients with vestibular dysfunction have balance disorders and vertigo, which may have a negative impact on the activities of daily living. This study aimed to investigate the effects of repetitive transcranial magnetic stimulation (TMS) on functional recovery in these patients.
Methods:
Thirty-five patients with unilateral peripheral vestibular dysfunction participated in this study. This study used a prospective randomised controlled trial design, and the randomisation was 1:1. They were randomly assigned to experimental and control groups; the experimental group, which consists of eighteen patients, received repetitive transcranial magnetic stimulation plus conventional physical therapy treatment in the form of Cawthorne-Cooksey exercises, while the control group, which consists of seventeen patients, received only conventional physical therapy treatment. The interventions in the two groups were conducted in three sessions every week for four consecutive weeks. The primary outcome measure was videonystagmography. The chi-squared and a mixed-design 2 × 2 MANOVA test were used to compare differences in variables for evaluating baseline and post-treatment changes.
Results:
The experimental group showed a significant improvement in canal weakness (66.26%) with a p < 0.001, DHI (77.21%) with a p-value of 0.001, and VADL (70.85%) with a p-value of 0.003 as compared to the controls. The control group showed significant improvements only in the DHI (44.45%) and VADL (33.05%) compared to the baseline, and the effect size f2 (V) = 0.66 was calculated for the independent canal weakness variable.
Conclusions:
The addition of repetitive transcranial magnetic stimulation to Cawthorne-Cooksey exercises could improve the outcomes of vestibular and self-rated functional recovery.
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