ORIGINAL PAPER
Effect of treadmill training on balance after chemotherapy in children with acute lymphoblastic leukaemia
 
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1
Department of Physical Therapy for Pediatrics, Faculty of Physical Therapy, Qena University, Qena, Egypt
 
2
Department of Physical Therapy for Musculoskeletal Disorders and Its Surgery, Faculty of Physical Therapy, Qena University, Qena, Egypt
 
3
Department of Physical Therapy for Basic Science, Faculty of Physical Therapy, Qena University, Qena, Egypt
 
4
Department of Physical Therapy for Neurology and Neurosurgery, Faculty of Physical Therapy, Qena University, Qena, Egypt
 
5
Department of Physical Therapy for Surgery, School of Health and Social Work, Physiotherapy Program, University of Hertfordshire Hosted by Global Academic Foundation, Cairo, Egypt
 
6
Department of Physical Therapy for Pediatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt
 
7
Rehabilitation Sciences Department, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia
 
 
Submission date: 2024-10-21
 
 
Acceptance date: 2025-05-19
 
 
Online publication date: 2026-03-06
 
 
Corresponding author
Ragaee Saeed Mahmoud   

Faculty of Physical Therapy, Qena University, Qena, Egypt
 
 
 
KEYWORDS
TOPICS
ABSTRACT
Introduction:
The goal of this study is to determine the efficacy of treadmill training in restoring balance after chemotherapy in children with acute lymphoblastic leukaemia (ALL).

Methods:
Sixty children of both sexes (29 boys and 31 girls), 8–12 years with acute lymphoblastic leukaemia, were randomly assigned to three equal groups. Group A (n = 20) was treated with medication only, group B (n = 20) was treated with a conventional physical therapy program and medication, and group C (n = 20) was treated with treadmill training and medication. The Master and Biodex Systems were used to assess balance among the three groups both pre- and post-intervention. The rehabilitation program was applied in 3 sessions weekly for 8 weeks.

Results:
The three groups demonstrated increasing improvements in all measurements, and the after-test mean values for all measurements revealed significant differences in favour of group B compared between groups A and B and in favour of group C compared between groups B and C (p < 0.05).

Conclusions:
Treadmill training was more effective than conventional physical therapy for improving balance in children with ALL after chemotherapy.
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